Guda:
Morphology:
Drug occurs in form of root stock with attached yellowish-brown stem portion, having 10 to 15 cm long, numerous grey to blackish-brown fibrous roots; solid, jointed, more or less cylindrical, 2 to 2.5 cm thick and varying in length, rough; fracture, splintery; odour and taste, not distinct.Histology:
Root Stock – Shows single layered epidermis followed by 3 to 4 layers of oval to elliptical, lignified, thick-walled more or less radially elongated, sclerenchymatous cells; cortex consists of upper 12 to 15 layers oval to polygonal, thin-walled and lower 5 layers, elliptical, parenchymatous cells; endodermis single layered; pericycle 3 or 4 layers, sclerenchymatous; fibro-vascular bundle, covered with sclerenchymatous sheath, scattered throughout the ground mass of parenchymatous cells.
Root – Shows single layered epidermis of thin-walled, rectangular cells, followed by a layer of hypodermis of thin-walled, rectangular cells, outer cortex composed of 2 or 3 layers of thick-walled, polygonal to circular, sclerenchymatous cells filled with dark brown or blackish pigment, inner cortex composed of large mrenchymatous cells; endodermis composed of barrel-shaped, thin-walled cells, enclosing a layer of pericycle consisting of rectangular cells having inner wall thickened, and vascular tissue; xylem and phloem form an equal number of separate bundles. arranged in a ring; centre occupied by a large pith, composed of circular to oval, parenchymatous, thin-walled cells
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