Chemical constituants of chatrii - Leea indica (Burm.f.) Merr., L..

chatrii :

Leea indica

Phytochemistry:


- Study of leaves of Leea indica yielded twenty-three known chemical compounds including 11 hydrocarbons, phthalic acid, palmitic acid, 1-eicosanol, solanesol, farnesol, three phthalic acid esters, gallic acid, lupeol, ß-sitosterol and ursolic acid. 
- Phytochemical screening isolation a novel carotenoid, leeatene, and nine other known compounds including squalene, hexadecanoyl-0-amyrin, vitamin E, 1 - tetratriacontanol, P-amyrin, 3-hydroxy-12-oleanen-28-oic acid, Psitosteryl- P-D-glucopyranoside, 2a,3a,23-trihydroxy-12-oleanen-28-oiacc id and phloridzin. 
- An ethanolic extract of roots yielded alkaloids, carbohydrates,steroids, triterpenoids, flavonoids, glycosides, anthraquinone glycosides, tannins, resins, and saponins. Chemical entities characterized included ß-sitosterol, lupeol, di-n-octyl phthalate, ß-amyrin, gallic acid, quercitrin, dibutyl phthalate and a-tocopheral. 
- Ethanol leaf extract yielded a total phenolic content of 24.00 ± 0.81 g GAE/100g, total flavonoid content of 194.68 ± 2.43 g quercetin/100g, and total antioxidant capacity of 106.61 ± 1.84 g AA/100 g dry extract. 
- Phytochemical screening of leaves yielded alkaloids, flavonoids, glycosides, phenols, lignins, saponins, sterols, tannins, arthraquinone, and reducing sugar. Methanol and ethanol extracts showed higher phenolic content than aqueous extract. 
- Crude methanol extract of leaves yielded alkaloids, glycosides, steroids, tannins, flavonoids, saponins, reducing sugars, and gums.


PHARMACOLOGY:

Important formulations 

1. Nagaradi taila 


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